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Updated: May 30, 2026

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
Published on: July 5, 2021
Olfactory groove meningioma
Nithin D Adappa1, John Y K Lee, Alexander G Chiu
1Department of Otorhinolaryngology-Head and Neck Surgery, University of Pennsylvania School of Medicine, Hospital of the University of Pennsylvania, Ravdin Building 5th Floor, 3400 Spruce Street, Philadelphia, PA 19104, USA. Nithin.Adappa@uphs.upenn.edu
Abstract:
Meningiomas are slow-growing benign tumors believed to originate from arachnoidal cap cells. This article discusses the surgical approaches for resection, especially the transnasal endoscopic approach. Alternative treatment options are primarily used where patients are not surgical candidates or location of recurrence precludes additional surgery. These options include radiotherapy, stereotactic radiosurgery, and chemotherapy. In addition, we discuss the current on going research in molecular targeting agents for meningioma treatment.
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