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09:53
Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
Published on: July 5, 2021
Olfactory groove meningioma.
Nithin D Adappa1, John Y K Lee, Alexander G Chiu
1Department of Otorhinolaryngology-Head and Neck Surgery, University of Pennsylvania School of Medicine, Hospital of the University of Pennsylvania, Ravdin Building 5th Floor, 3400 Spruce Street, Philadelphia, PA 19104, USA. Nithin.Adappa@uphs.upenn.edu
Otolaryngologic Clinics of North America
|August 9, 2011
Summary
Meningiomas, slow-growing tumors, are best treated with surgical resection, particularly the transnasal endoscopic approach. Radiotherapy and chemotherapy are alternatives for non-surgical candidates or recurrent cases, with ongoing research into molecular targeting agents.
Area of Science:
- Neurosurgery
- Oncology
Background:
- Meningiomas are typically benign, slow-growing tumors originating from arachnoidal cap cells.
- Surgical resection is the primary treatment modality for most meningiomas.
Purpose of the Study:
- To review surgical approaches for meningioma resection.
- To discuss alternative treatments and ongoing research for meningioma management.
Main Methods:
- Discussion of surgical techniques, focusing on the transnasal endoscopic approach.
- Review of non-surgical options including radiotherapy, stereotactic radiosurgery, and chemotherapy.
- Exploration of current research in molecular targeting agents for meningioma treatment.
Main Results:
- The transnasal endoscopic approach offers a viable surgical option for meningioma resection.
- Radiotherapy, stereotactic radiosurgery, and chemotherapy serve as important alternatives.
- Molecular targeting agents represent a promising area for future meningioma therapies.
Conclusions:
- Surgical resection, especially the transnasal endoscopic approach, is a key treatment for meningiomas.
- Alternative treatments are crucial for specific patient populations and recurrent disease.
- Further research into molecular therapies holds potential for advancing meningioma treatment.
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