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Updated: May 30, 2026

Sectioning Mammary Gland Whole Mounts for Lesion Identification
Published on: July 24, 2017
Complex mammary adenoma with sebaceous differentiation in a dog
A G Kurilj1, M Hohšteter, A Beck
1Department of Veterinary Pathology, Faculty of Veterinary Medicine, University of Zagreb, Heinzelova 55, Zagreb 10000, Croatia. agudan@vef.hr
Abstract:
Sebaceous metaplasia arising within a complex adenoma of the left fourth mammary gland is described in a 9-year-old miniature pinscher bitch. Microscopically, the tumour was composed of tubular and ductular structures admixed with clusters of spindle-shaped, myoepithelial-like cells and units formed of well-differentiated sebocytes surrounded by basaloid cells. Abundant lipid droplets were identified within the latter population by Sudan III staining. Immunohistochemical expression of cytokeratin AE1/AE3 was detected in epithelial cells and in the cells with sebaceous differentiation.
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