Related Experiment Video
Updated: May 30, 2026

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
Published on: May 26, 2023
Fifteen-year experience with minimally invasive approach for reoperations involving the mitral valve
Joseph M Arcidi1, Evelio Rodriguez, Joseph R Elbeery
1Department of Cardiovascular Sciences, East Carolina University, 600 Moye Blvd, Greenville, NC 27858, USA.
Objective:
Reoperative sternotomy to address mitral valve pathology carries substantial risk, especially with patent bypass grafts or an aortic valve prosthesis. We previously reported our early experience with minimally invasive right thoracotomy and peripheral cannulation as an alternative strategy, and we recently reviewed our cumulative 15-year hospital outcomes with this approach.
Methods:
Between June 1996 and April 2010, we performed right minithoracotomy for reoperations involving the mitral valve on 167 patients, 85 (51%) of these since 2006. Seventy-one percent had undergone previous coronary artery bypass grafting and 38% a previous valve procedure. Fibrillatory arrest was used in 77% and aortic clamping and root cardioplegia in 23%. Nineteen procedures were performed with robotic assistance.
Results:
Mitral repair frequency increased during each 5-year interval of our experience (1996-2000, 43%; 2001-2005, 53%; 2006-2010, 72%; P = .019), including 80% of native mitral valves without stenosis. Concomitant procedure frequency, most commonly atrial fibrillation ablation, also increased during each 5-year interval (0%, 21%, 48%; P < .0001). Thirty-day mortality was 3.0% (5/167), 0% since 2005. There were no conversions to sternotomy or aortic dissections. Stroke, in 2.4% (4/167), was statistically unrelated to fibrillatory arrest. Increased New York Heart Association functional class (odds ratio, 5.6; 95% confidence interval 1.1-27.8; P = .037) was the only independent predictor of mortality in multivariable analysis.
Conclusions:
Our updated experience confirmed the effectiveness of minimally invasive right thoracotomy to treat mitral pathology while avoiding reoperative sternotomy risk. We found fibrillatory and cardioplegic arrest methods to be safe myocardial preservation strategies with this approach.
Insights
Minimally invasive right thoracotomy is a safe and effective alternative to sternotomy for mitral valve reoperations, reducing mortality and stroke risk. This approach, utilizing fibrillatory or cardioplegic arrest, demonstrates improved outcomes over 15 years.
Area of Science:
- Cardiovascular Surgery
- Thoracic Surgery
- Minimally Invasive Procedures
Background:
- Reoperative sternotomy for mitral valve pathology poses significant risks, particularly with prior bypass grafts or aortic valve prostheses.
- Minimally invasive right thoracotomy with peripheral cannulation offers an alternative strategy to avoid sternotomy risks.
Purpose of the Study:
- To review cumulative 15-year hospital outcomes of minimally invasive right thoracotomy for mitral valve reoperations.
- To assess the safety and effectiveness of this approach compared to traditional sternotomy.
Main Methods:
- A retrospective review of 167 patients undergoing right minithoracotomy for mitral valve reoperations between June 1996 and April 2010.
- Analysis of patient demographics, previous surgical history, myocardial preservation techniques (fibrillatory arrest vs. aortic clamping/cardioplegia), and robotic assistance.
- Evaluation of procedural outcomes, including mitral repair rates, concomitant procedures, mortality, stroke, and conversions to sternotomy.
Main Results:
- Mitral repair frequency increased significantly over time (43% to 72%), especially for native valves (80%).
- Concomitant procedures, such as atrial fibrillation ablation, also increased (0% to 48%).
- Thirty-day mortality was 3.0% overall, with 0% reported since 2005. Stroke occurred in 2.4% of patients. Increased NYHA functional class was the only independent predictor of mortality.
Conclusions:
- Minimally invasive right thoracotomy is an effective strategy for treating mitral valve pathology, successfully avoiding the risks associated with reoperative sternotomy.
- Both fibrillatory and cardioplegic arrest methods are safe myocardial preservation techniques for this minimally invasive approach.
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