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Published on: December 9, 2022
Patient-reported symptoms are independent of disease severity in patients with primary varicose veins
A M Conway1, I M Nordon, R J Hinchliffe
1St George's Vascular Institute, St George's Healthcare NHS Trust, London SW17 0QT, UK. allan.m.conway@doctors.org.uk
Insights
Chronic venous disorder symptoms do not always correlate with disease severity. Advanced venous disease impacts quality of life, indicating objective scores like CEAP are crucial for patient management.
Area of Science:
- Vascular Medicine
- Medical Diagnostics
Background:
- Chronic venous disorders (CVD) encompass a spectrum of conditions affecting venous function.
- Accurate patient stratification is essential for effective referral and treatment pathways.
Purpose of the Study:
- To investigate the relationship between chronic venous disorder symptoms and disease distribution.
- To correlate findings with the CEAP classification and presenting symptoms.
- To identify features guiding patient referral and treatment for CVD.
Main Methods:
- Consecutive patients (424 limbs) from a university hospital's venous clinic were assessed over 12 months.
- Patients underwent clinical evaluation, CEAP scoring, and duplex ultrasonography.
- Data were analyzed to find associations between symptoms and disease severity (CEAP C2-6).
Main Results:
- Symptom presentation, such as ache, was independent of CEAP classification.
- Advanced CVD (CEAP C4-6) was linked to older age, larger varicose vein diameter, and lower quality of life (AVVS).
- Saphenofemoral junction reflux correlated with ache and pain.
Conclusions:
- Chronic venous disorder symptoms do not reliably predict disease severity based on CEAP score alone.
- Objective markers including CEAP, Venous Clinical Severity Score, and AVVS are vital for determining patient management pathways.
- Gender and CEAP classification influenced treatment decisions, with women in earlier stages more likely to receive surgery.
Abstract:
The objective of this paper is to explore patterns of incompetence and disease distribution in patients with chronic venous disorders and to correlate this with CEAP (Clinical, Etiologic, Anatomic and Pathologic) classification and presenting symptoms to determine which features of chronic venous disorder (CVD) could be used to guide a patient pathway for referral and treatment. Consecutive patients attending a one-stop venous clinic at a university teaching hospital were recruited over a 12-month period. Patients were clinically assessed, assigned CEAP scores, duplex-scanned and categorized. Data were analyzed to identify associations between symptomatology and disease. Four hundred twenty-four limbs were divided into groups A (C2-3) (339) and B (C4-6) (85). The number of men, mean patient age, varicose vein diameter and quality-of-life score (Aberdeen Varicose Vein Questionnaire - AVVS) were significantly higher in group B (P < 0.01). Ache occurred more commonly in group A and in women (P < 0.01). Ache and pain were seen more frequently with saphenofemoral junction reflux (P < 0.05). Group A women were more likely to be offered surgical intervention while men were managed conservatively (P < 0.05). In conclusion, CVD symptoms are independent of disease severity assessed by CEAP score. Advanced disease is associated with larger venous diameters, older age and corresponds to a poorer quality of life. Objective markers such as CEAP, Venous Clinical Severity Score and AVVS should be used in determining a patient pathway for referral and treatment of CVD.
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