Post-transplantation encapsulating peritoneal sclerosis in a young child

Ratna Tan1, Michiel Betjes, Karlien Cransberg

  • 1Department of Children Nephrology, Sophia Children’s Hospital, Erasmus MC, Rotterdam, Netherlands.

Insights

Encapsulating peritoneal sclerosis (EPS) is a rare condition in children undergoing peritoneal dialysis (PD). Prompt diagnosis via CT scan and treatment including PD cessation and nutritional support are crucial for managing bowel obstruction symptoms.

Area of Science:

  • Pediatric Nephrology
  • Gastroenterology
  • Surgical Complications

Background:

  • Encapsulating peritoneal sclerosis (EPS) is a rare but serious complication in children, particularly those with a history of peritoneal dialysis (PD).
  • Clinical presentation often mimics bowel obstruction, necessitating a high index of suspicion in affected pediatric patients.
  • Post-transplantation EPS represents a specific subset of this condition requiring tailored management strategies.

Observation:

  • This report details a case of a pediatric patient who developed EPS following a kidney transplant.
  • The patient presented with symptoms consistent with bowel obstruction, prompting further investigation.
  • Diagnostic imaging, specifically CT scan, played a pivotal role in confirming the diagnosis.

Findings:

  • Prompt diagnosis of EPS in children with a history of PD is critical.
  • Management involves immediate cessation of PD, if applicable.
  • Nutritional support, either parenteral or enteral, is a cornerstone of treatment.

Implications:

  • Early recognition and intervention for EPS in pediatric patients can significantly alter outcomes.
  • The role of medical therapies, including steroids and calcineurin inhibitor adjustment, requires further investigation.
  • This case highlights the importance of considering EPS in the differential diagnosis of bowel obstruction in children with PD history.

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