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Post-transplantation encapsulating peritoneal sclerosis in a young child
Ratna Tan1, Michiel Betjes, Karlien Cransberg
1Department of Children Nephrology, Sophia Children’s Hospital, Erasmus MC, Rotterdam, Netherlands.
Insights
Encapsulating peritoneal sclerosis (EPS) is a rare condition in children undergoing peritoneal dialysis (PD). Prompt diagnosis via CT scan and treatment including PD cessation and nutritional support are crucial for managing bowel obstruction symptoms.
Area of Science:
- Pediatric Nephrology
- Gastroenterology
- Surgical Complications
Background:
- Encapsulating peritoneal sclerosis (EPS) is a rare but serious complication in children, particularly those with a history of peritoneal dialysis (PD).
- Clinical presentation often mimics bowel obstruction, necessitating a high index of suspicion in affected pediatric patients.
- Post-transplantation EPS represents a specific subset of this condition requiring tailored management strategies.
Observation:
- This report details a case of a pediatric patient who developed EPS following a kidney transplant.
- The patient presented with symptoms consistent with bowel obstruction, prompting further investigation.
- Diagnostic imaging, specifically CT scan, played a pivotal role in confirming the diagnosis.
Findings:
- Prompt diagnosis of EPS in children with a history of PD is critical.
- Management involves immediate cessation of PD, if applicable.
- Nutritional support, either parenteral or enteral, is a cornerstone of treatment.
Implications:
- Early recognition and intervention for EPS in pediatric patients can significantly alter outcomes.
- The role of medical therapies, including steroids and calcineurin inhibitor adjustment, requires further investigation.
- This case highlights the importance of considering EPS in the differential diagnosis of bowel obstruction in children with PD history.
Abstract:
Encapsulating peritoneal sclerosis (EPS) is a very rare condition in children. Nevertheless, EPS should be considered when a child with a history of peritoneal dialysis (PD) presents with signs of bowel obstruction. We describe a child with post-transplantation EPS and discuss risk factors, diagnosis and treatment options. CT scan should be performed promptly to confirm the diagnosis. Treatment consists of cessation of the PD, if applicable, and adequate nutrition, either parenteral or enteral. Further medical therapy remains controversial but may involve steroids and/or interruption of calcineurin inhibitors.
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