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Updated: May 30, 2026

Intracoronary Acetylcholine Provocation Testing for Assessment of Coronary Vasomotor Disorders
Published on: August 18, 2016
Accelerated coronary atherosclerosis revealed by arrhythmogenic coronary spasm
Franck Sibellas1, Nicolas Girerd, Theodora Bejan-Angoulvant
1Intensive Care Unit, Hospices Civils de Lyon, Louis Pradel Cardiovascular Hospital, Lyon, France.
Abstract:
Coronary artery spasm is sometimes associated with life-threatening ventricular arrhythmias. Based on intravascular ultrasound findings, it appears that coronary artery spasm promotes negative arterial remodeling, suggesting that patients with coronary artery spasm might be at higher risk of accelerated coronary atherosclerosis. We report the cases of 3 patients with ventricular arrhythmia secondary to coronary artery spasm complicated by accelerated coronary atherosclerosis. Consequently, coronary disease progression should be considered in the case of angina pectoris recurrence in patients with coronary artery spasm, especially in those with coronary artery spasm complicated by ventricular arrhythmia.
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