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Related Experiment Video

Updated: May 30, 2026

Description of a Swine Infant Model of Volume-Controlled Hemorrhagic Shock

Description of a Swine Infant Model of Volume-Controlled Hemorrhagic Shock

Published on: November 3, 2023

Little boy black and blue.

Amanda E Greene¹, Genie E Roosevelt, Joseph A Grubenhoff

¹Section of Emergency Medicine, Department of Pediatrics, University of Colorado, Denver, Aurora, CO 80045, USA. greene.amanda@tchden.org

Pediatric Emergency Care

|August 9, 2011

Summary

Pediatric tooth decay is rising, leading to more children needing root canals. A rare complication from sodium hypochlorite toxicity during a pediatric root canal is presented.

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Area of Science:

Pediatric Dentistry
Endodontics
Toxicology

Background:

Tooth decay is a prevalent issue among US children, disproportionately affecting those from low-income households.
Over half of second-grade children experience cavities, increasing the need for pediatric root canal treatments.
Root canal procedures in children are becoming more frequent due to rising rates of dental caries.

Observation:

A case report details a rare complication following a root canal procedure in a 2-year-old boy.
The complication was identified as sodium hypochlorite toxicity.
Sodium hypochlorite is a standard irrigant used in root canal therapies.

Findings:

The study highlights a severe adverse event linked to sodium hypochlorite, a common endodontic irrigant.
This case underscores the potential for toxicity even with widely used dental materials.
Review of sodium hypochlorite toxicity in the context of endodontic procedures is provided.

Implications:

This case emphasizes the importance of careful technique and awareness of potential complications during pediatric endodontic procedures.
Understanding sodium hypochlorite toxicity is crucial for pediatric dentists performing root canals.
Further research may be warranted to explore safer irrigant alternatives or protocols for managing toxicity in pediatric patients.