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Treatment of Pediatric Bipolar Disorder: A Review
Jason J Washburn1, Amy E West, Jennifer A Heil
1Northwestern University Feinberg School of Medicine, Department of Psychiatry and Behavioral Sciences.
Insights
This review covers diagnosing and treating pediatric bipolar disorder (PBD). It examines medication options like Lithium and antipsychotics, alongside psychosocial interventions, highlighting remaining knowledge gaps.
Area of Science:
- Child and Adolescent Psychiatry
- Neuroscience
- Psychopharmacology
Background:
- Pediatric bipolar disorder (PBD) presents diagnostic challenges.
- Understanding PBD's complexities is crucial for effective treatment.
Purpose of the Study:
- To review current diagnostic approaches for PBD.
- To evaluate pharmacologic and psychosocial interventions for PBD.
Main Methods:
- Comprehensive literature review of PBD diagnosis and treatment studies.
- Analysis of evidence for various treatment modalities.
Main Results:
- Discusses diagnostic controversies and an evidence-based assessment protocol.
- Reviews evidence for Lithium, antiepileptics, and second-generation antipsychotics.
- Examines existing psychosocial treatments for PBD.
Conclusions:
- Recent advances in PBD understanding and treatment exist.
- Significant gaps in knowledge regarding PBD diagnosis and treatment persist.
Abstract:
AIM: To review the diagnosis and the pharmacologic and psychosocial interventions for pediatric bipolar disorder (PBD). METHODS: A comprehensive literature review of studies discussing the diagnosis and treatment of PBD was conducted. RESULTS: A context for understanding controversies and difficulties in the diagnosis of PBD is provided. An evidence-based assessment protocol for PBD is reviewed. The evidence for the following three categories of pharmacologic interventions are reviewed: Lithium, antiepileptics, and second generation antipsychotics. Algorithms for medication decisions are briefly reviewed. Existing psychosocial treatments and the evidence for those treatments are also reviewed. CONCLUSION: Despite recent developments in understanding the phenomenology of PBD and in identifying pharmacologic and psychosocial interventions, critical gaps remain.
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