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Updated: May 30, 2026

A Fish-feeding Laboratory Bioassay to Assess the Antipredatory Activity of Secondary Metabolites from the Tissues of Marine Organisms
Published on: January 11, 2015
A new hydroxylated nonaprenylhydroquinone from the Mediterranean marine sponge Sarcotragus spinosulus
Charline Abed1,2, Nathalie Legrave1, Maeva Dufies3
1Chemistry Laboratory of Biomolecules and Aroma, Nice Institute of Chemistry, UFR of Sciences, University of Nice-Sophia Antipolis, UMR-CNRS 6001, Parc Valrose, F-06108 Nice Cedex 02, France.
Abstract:
Chemical investigation of the Mediterranean sponge Sarcotragus spinosulus led to the isolation of a new hydroxylated nonaprenylhydroquinone, along with two known metabolites, hepta- and octaprenylhydroquinones. The structure of the new metabolite was assigned by extensive 1D and 2D NMR analyses and MS studies. The antileukemic effect of the three compounds towards the chronic myelogenous leukemia (CML) cells line K562 was also evaluated.

