Related Experiment Video
Updated: May 30, 2026
05:52
Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy
Published on: August 19, 2021
Microsatellite instability analysis in uterine cavity washings as a screening tool for endometrial cancer in Lynch
Julie Bouquier1, Hélène Blons, Céline Narjoz
1Université Paris Descartes, Paris, France.
Familial Cancer
|August 9, 2011
Abstract:
Although patients with Lynch syndrome (LS) are at high risk of endometrial cancer, gynecologic screening has been poorly investigated and diagnostic value of current screening tests remains unclear. Microsatellite instability (MSI) phenotype is found in more than 90% of endometrial cancers developed in LS patients. Here we report the first two cases of unstable endometrial tumors with detection of MSI in uterine cavity washings cells. This new technique may be a promising screening tool in LS.
