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Updated: May 30, 2026

Design and Implementation of an fMRI Study Examining Thought Suppression in Young Women with, and At-risk, for Depression
Published on: May 19, 2015
Disentangling the prospective relations between maladaptive cognitions and depressive symptoms
Beth LaGrange1, David A Cole, Farrah Jacquez
1Department of Psychology and Human Development, Vanderbilt University, Nashville, TN 37203-5721, USA.
Depression in children and adolescents predicts negative thinking patterns, not the other way around. This relationship strengthens with age, offering insights for targeted mental health interventions.
Area of Science:
- Child and adolescent psychology
- Developmental psychopathology
- Cognitive behavioral science
Background:
- Understanding the interplay between thoughts and emotions is crucial for child mental health.
- Longitudinal studies are essential to establish predictive relationships in developmental trajectories.
- Previous research suggests a link between cognition and depression, but the directionality and developmental course require further investigation.
Purpose of the Study:
- To investigate the longitudinal structure of maladaptive cognitions and depressive symptoms in children and adolescents.
- To examine the prospective, directional relationship between maladaptive cognitions and depressive symptoms over time.
- To explore how age influences the association between cognitive patterns and depression.
Main Methods:
- A four-wave, cohort-longitudinal study design.
- Inclusion of a community sample of 515 children and adolescents (grades 2-9).
- Application of multigroup structural equation modeling to analyze data.
Main Results:
- Both maladaptive cognitions and depressive symptoms exhibited stable (time-invariant) and changing (time-varying) components over time.
- Depressive symptoms prospectively predicted maladaptive cognitions, but not vice versa.
- The stable aspects of cognition and depression were strongly correlated.
- The predictive effect of depression on cognition increased with age.
Conclusions:
- Depression appears to be a significant predictor of negative thinking styles in youth.
- The findings highlight the importance of addressing depressive symptoms early to potentially mitigate the development of maladaptive cognitions.
- Interventions targeting depression in children and adolescents may benefit from considering the age-related intensification of this cognitive-emotional link.
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