Genetically manipulated adult stem cells for wound healing
Related Experiment Video
Updated: May 30, 2026

Creation and Transplantation of an Adipose-derived Stem Cell (ASC) Sheet in a Diabetic Wound-healing Model
Published on: August 4, 2017
Li-Hua Peng1, Kwok-Pui Fung, Ping-Chung Leung
1Institute of Pharmaceutics, College of Pharmaceutical Sciences, Zhejiang University, PR China.
Abstract:
New knowledge of the signal controls and activities of adult stem cells (ASCs) involved in wound repair have led to extensive investigation of the topical delivery of biomacromolecules and multipotent stem cells to injured tissues for scar-less regeneration. The transplantation of genetically recombinant stem cells, which have roles as both therapeutics and carriers for gene delivery to wound sites, represents an attractive strategy for wound treatment. Here, we compare viral and non-viral vectors and three-dimensional scaffold-based transfection strategies in terms of their biosafety, recombinant efficiency and influence on the differentiation of ASCs, to indicate the future direction of the application of recombinant ASCs in wound treatment.
Related Concept Videos
Stem Cell Culture
Stem Cell Therapy for Tissue Regeneration
Types of Stem Cells used in Stem Cell Therapy
The two main cell types that...
Adult Stem Cells
Clinical Applications of Epidermal Stem Cells
iPS Cell Differentiation
Mesenchymal Stem Cells

