Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Varicose Veins II: Diagnostic Studies and Interprofessional Care

Varicose Veins II: Diagnostic Studies and Interprofessional Care

Varicose veins, or varicosities, develop when the valves in the veins, which control blood flow, weaken or damage. It causes blood to pool and the veins to enlarge. Understanding the clinical manifestations, diagnostic approaches, and management options for varicose veins is crucial for effective treatment and relief.Clinical manifestationsClinical manifestations of varicose veins include a heavy, achy feeling or pain after prolonged standing or sitting. This discomfort can often be relieved by...

Varicose Veins I: Introduction

Varicose Veins I: Introduction

Varicose veins, or varicosities, are abnormally dilated and twisted superficial veins caused by venous valve incompetence. This condition commonly affects the lower extremities, especially the saphenous veins, due to the higher pressure from prolonged standing and walking. However, varicosities can also occur in other areas, such as the esophagus, vulva, spermatic cords, and anorectal region.Etiology and typesPrimary varicose veins, often idiopathic, are more common in women due to inherent...

Esophageal Varices-II: Clinical Features and Management

Esophageal Varices-II: Clinical Features and Management

Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol abuse, or...

Clinical Applications of Epidermal Stem Cells

Clinical Applications of Epidermal Stem Cells

Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own EpiSCs...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Development of international clinical practice guidelines: benefits, limitations, and alternative forms of international collaboration.

Archives of dermatological research·2020

Same author

Principles for developing and adapting clinical practice guidelines and guidance for pandemics, wars, shortages, and other crises and emergencies: the PAGE criteria.

Archives of dermatological research·2020

Same author

Broad versus narrow clinical practice guidelines: avoiding rules for the high risk 1.

Archives of dermatological research·2020

Same author

Sebaceous carcinoma: evidence-based clinical practice guidelines.

The Lancet. Oncology·2019

Same author

An expert panel consensus on opioid-prescribing guidelines for dermatologic procedures.

Journal of the American Academy of Dermatology·2019

Same author

Characterization of the facial microbiome in twins discordant for rosacea.

Experimental dermatology·2017

Search research articles

Related Experiment Video

Updated: May 30, 2026

Endoscopic Injection Sclerotherapy Assisted by Cyanoacrylate and Clips for Gastroesophageal Varices

Endoscopic Injection Sclerotherapy Assisted by Cyanoacrylate and Clips for Gastroesophageal Varices

Published on: June 13, 2025

Sclerotherapy: it is back and better.

Margaret W Mann¹

¹Department of Dermatology, University of California, C340 Medical Sciences I, Irvine, CA 92697, USA. margaret.mann@gmail.com

Clinics in Plastic Surgery

|August 10, 2011

Summary

This summary is machine-generated.

Sclerotherapy, a gold standard for spider and reticular veins, is gaining new interest with FDA-approved polidocanol. Modern techniques and agents enhance the safety and efficacy of this long-standing treatment.

More Related Videos

Underwater Endoscopic Injection Sclerotherapy for Gastroesophageal Varices

Underwater Endoscopic Injection Sclerotherapy for Gastroesophageal Varices

Published on: August 1, 2025

Combination of High Ligation and Intraoperative Embolization Using Polidocanol for Treatment of Varicoceles

Combination of High Ligation and Intraoperative Embolization Using Polidocanol for Treatment of Varicoceles

Published on: December 22, 2023

Related Experiment Videos

Last Updated: May 30, 2026

Endoscopic Injection Sclerotherapy Assisted by Cyanoacrylate and Clips for Gastroesophageal Varices

Endoscopic Injection Sclerotherapy Assisted by Cyanoacrylate and Clips for Gastroesophageal Varices

Published on: June 13, 2025

Underwater Endoscopic Injection Sclerotherapy for Gastroesophageal Varices

Underwater Endoscopic Injection Sclerotherapy for Gastroesophageal Varices

Published on: August 1, 2025

Combination of High Ligation and Intraoperative Embolization Using Polidocanol for Treatment of Varicoceles

Combination of High Ligation and Intraoperative Embolization Using Polidocanol for Treatment of Varicoceles

Published on: December 22, 2023

Area of Science:

Vascular Medicine
Dermatology
Minimally Invasive Procedures

Background:

Sclerotherapy is the established gold standard for treating superficial spider and reticular veins.
Recent FDA approval of polidocanol has renewed interest in sclerotherapy.
Advancements in sclerosants and techniques improve treatment safety and efficacy.

Purpose of the Study:

To provide a comprehensive overview of sclerotherapy for physicians.
To update medical professionals on modern sclerotherapy practices.
To highlight recent advancements in vein treatment.

Main Methods:

Review of common sclerosant agents.
Discussion of contemporary sclerotherapy techniques.
Guidance on patient evaluation and complication management.

Main Results:

Sclerotherapy remains highly effective for spider and reticular veins.
Newer agents and techniques increase safety and patient outcomes.
Polidocanol approval signifies a resurgence in sclerotherapy utilization.

Conclusions:

Sclerotherapy is a safe and effective treatment option for venous conditions.
Physicians can benefit from updated knowledge on sclerotherapy.
Continued advancements promise further improvements in sclerotherapy outcomes.