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Related Experiment Video

Updated: May 30, 2026

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
06:39

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants

Published on: June 13, 2021

Does weight gain during pregnancy influence postpartum depression?

Krista M C Cline1, Jessica Decker

  • 1Butler University, 4600 Sunset Blvd., Jordan Hall Room 371A, Indianapolis, IN 46208, USA. kcline1@butler.edu

Journal of Health Psychology
|August 10, 2011
PubMed
Summary

Pregnancy weight gain may impact postpartum depression (PPD). For obese women, less weight gain was linked to higher PPD risk, suggesting a complex relationship between maternal weight and mental health.

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Using Chronic Social Stress to Model Postpartum Depression in Lactating Rodents
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Last Updated: May 30, 2026

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
06:39

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants

Published on: June 13, 2021

Using Chronic Social Stress to Model Postpartum Depression in Lactating Rodents
07:30

Using Chronic Social Stress to Model Postpartum Depression in Lactating Rodents

Published on: June 10, 2013

Area of Science:

  • Obstetrics and Gynecology
  • Perinatal Mental Health
  • Maternal-Fetal Medicine

Background:

  • Postpartum depression (PPD) is a significant concern affecting new mothers.
  • The role of pregnancy weight gain in PPD risk is not fully understood.
  • Obesity is a known risk factor for various health conditions, including mental health issues.

Purpose of the Study:

  • To investigate the association between pregnancy weight gain and the incidence of postpartum depression (PPD).
  • To explore potential differences in this association based on pre-pregnancy body weight categories.

Main Methods:

  • A web-based survey was administered to 238 women who recently gave birth.
  • Data analysis included the total sample and stratified analyses by pre-pregnancy body weight.
  • Statistical methods were used to identify predictors of PPD.

Main Results:

  • A significant inverse association was found between weight gain during pregnancy and PPD among obese women.
  • For obese participants, lower gestational weight gain correlated with a higher likelihood of experiencing PPD.
  • History of depression, perceived partner support, and maternal age were also identified as significant predictors of PPD.

Conclusions:

  • Pregnancy weight gain may have a differential impact on PPD risk, particularly for obese women.
  • Lower gestational weight gain in obese women could be an indicator for increased PPD vulnerability.
  • Further research is warranted to elucidate the mechanisms underlying this relationship and inform targeted interventions.