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Internet and print resources to facilitate pathology analysis when phenotyping genetically engineered rodents
1The Ohio State University, Department of Veterinary Biosciences, 350 Veterinary Medicine Academic Building, 1900 Coffey Road, Columbus, OH 43210, USA. Brad.Bolon@cvm.osu.edu
Veterinary Pathology
|August 10, 2011
Summary
Genetically engineered rodents are vital disease models. Cataloging their full spectrum of changes is crucial for understanding mutations and their relevance to human diseases, aiding research with annotated resources.
Area of Science:
- Biomedical Research
- Genetics
- Pathology
Background:
- Genetically engineered rodents (mice and rats) are essential models for studying disease mechanisms.
- Comprehensive phenotyping is required to understand mutation significance for human diseases.
- Existing reference materials aid researchers in phenotyping new rodent models.
Purpose of the Study:
- To provide an annotated register of resources for the pathology component of rodent phenotyping.
- To assist researchers in quickly determining the relevance of resources to their specific projects.
Main Methods:
- Compilation of reference materials.
- Annotation of frequently used resources by the authors.
- Focus on pathology-related resources for rodent phenotypic analysis.
Main Results:
- An extensive register of pathology-related resources for rodent phenotyping is presented.
- Annotations facilitate efficient resource selection for research projects.
Conclusions:
- Annotated resources streamline the phenotyping process for genetically engineered rodents.
- This compilation supports accurate extrapolation of findings to human diseases.
