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Updated: May 30, 2026

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Synthesis of Functionalized Magnetic Nanoparticles, Their Conjugation with the Siderophore Feroxamine and its Evaluation for Bacteria Detection
Published on: June 16, 2020
SiO2@Fe2O3 core-shell nanoparticles for covalent immobilization and release of sparfloxacin drug
Nadia E A El-Gamel1, Laura Wortmann, Karim Arroub
1Chemistry Department, Faculty of Science, Cairo University, 12613 Giza, Egypt. nadinealy@hotmail.com
Abstract:
Silica-coated Fe(2)O(3) nanoparticles were synthesized as carriers for the covalent immobilization and release of antimicrobial drug sparfloxacin (SPFX). SPFX-loaded nanoparticles exhibited time-dependent drug release, with no measurable in vitro cytotoxicity, making the drug@nanoparticle conjugates potentially relevant for nanomedicine applications.

