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Updated: May 30, 2026

Identification of Virulence Markers of Mycobacterium abscessus for Intracellular Replication in Phagocytes

Identification of Virulence Markers of Mycobacterium abscessus for Intracellular Replication in Phagocytes

Published on: September 27, 2018

Multiple amoebic abscesses with erythema nodosum.

Gayathri Satish¹, L Rajam, Sukhmani Regi

¹Department of Pediatrics, Amrita Institute of Medical Sciences and Research Centre, Amrita Lane, AIMS Ponekkara Post, Kochi, Kerala, India. gayathrisatish2004@yahoo.com

Indian Journal of Pediatrics

|August 11, 2011

Summary

A rare case of extraintestinal amoebiasis in a child presented with multiple liver, spleen, and kidney abscesses. This report highlights a unique association between erythema nodosum and this severe parasitic infection in pediatric patients.

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Last Updated: May 30, 2026

Identification of Virulence Markers of Mycobacterium abscessus for Intracellular Replication in Phagocytes

Identification of Virulence Markers of Mycobacterium abscessus for Intracellular Replication in Phagocytes

Published on: September 27, 2018

Area of Science:

Tropical medicine
Pediatric infectious diseases
Parasitology

Background:

Amoebiasis is a prevalent parasitic infection in tropical regions, typically presenting as a solitary liver abscess.
Extraintestinal amoebiasis, particularly with multiple organ involvement, is uncommon in children.

Observation:

A 6-year-old girl experienced a febrile illness accompanied by hepatosplenomegaly and erythema nodosum.
Imaging and aspiration cytology confirmed multiple amoebic abscesses in the liver, spleen, and kidneys.

Findings:

The patient was diagnosed with a rare, disseminated form of extraintestinal amoebiasis.
This case represents the first documented instance of erythema nodosum associated with extraintestinal amoebiasis in a pediatric patient.

Implications:

This case expands the known clinical spectrum of extraintestinal amoebiasis in children.
Recognizing this rare presentation is crucial for timely diagnosis and management of severe amoebic infections in pediatric populations.
The association with erythema nodosum may serve as an important diagnostic clue in endemic areas.