Related Experiment Video
Updated: May 30, 2026
Establishment and Evaluation of a Risk Prediction Model for Pathological Escalation of Gastric Low-Grade Intraepithelial Neoplasia
Published on: February 16, 2024
Differences in prognostic factors between early and advanced gastric cancer
Byung Seup Kim1, Sung Wook Cho, Soo Kee Min
1Department of Surgery, Hallym University College of Medicine, Anyang, Korea.
Background/Aims:
The aim of this study was to assess any differences in the prognostic factors affecting long term survival in early gastric cancer (EGC) and advanced gastric cancer (AGC).
Methodology:
The prognostic factors affecting long term survival between EGC and AGC were evaluated.
Results:
Based on the result of multivariate analysis, the variables related with poor prognosis in patient with EGC were ages of more than 60 (p=0.003, Relative risk [RR]:2.683) and more than 7 lymph nodes with metastasis (p=0.001, RR:12.129). The relevant variables in AGC were the presence of more than 7 lymph nodes with metastasis (p=0.002, RR:2.491), lymphovascular invasion (p=0.038, RR:1.476) and tumor depth (serosa ; p<0.001, RR:3.493, adjacent structure; p=0.005, RR:3.013).
Conclusions:
The prognostic factors affecting long term survival are a little different between the patients with EGC and AGC. Age of more than 60 years is one of the prognostic factors affecting long term survival in patients with EGC, but not with AGC. In AGC, lymphovascular invasion and tumor depth are prognostic factors but not in EGC.
Related Concept Videos
01:21Cancer Survival Analysis
01:20Comparing the Survival Analysis of Two or More Groups
02:07Tumor Progression
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...