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Related Concept Videos

Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own EpiSCs...
Renewal of Skin Epidermal Stem Cells01:12

Renewal of Skin Epidermal Stem Cells

The skin is divided into epidermis, dermis, and hypodermis, the skin's outermost, middle, and inner layers. The human epidermal layer regularly undergoes renewal, where old, dead cells are replaced by new cells. Epidermal stem cells or EpiSCs divide and differentiate to restore the lost cells. For the renewal process, some EpiSCs continuously self-renew. In contrast, few others differentiate into transit-amplifying cells, which later form prickle or spinous cells, followed by granular cells,...
Pigmentation01:19

Pigmentation

The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
Cells of the Epidermis01:24

Cells of the Epidermis

The epidermis is made of four or five layers of epithelial cells, depending on its location in the body. From deep to superficial, these layers are the stratum basale, stratum spinosum, stratum granulosum, stratum lucidum, and stratum corneum.
The cells in all these layers except the stratum basale are called keratinocytes, a type of cell that manufactures and stores the protein keratin. The keratinocytes in the stratum corneum are dead and regularly slough away, being replaced by cells from...

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Enhancement of Facial Rejuvenation Through a Combination of 1565 nm Non-Ablative Fractional Laser with 30% Supramolecular Salicylic Acid
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Chemical peelings--when and why?

Lenka Oremović1, Zeljana Bolanca, Mirna Situm

  • 1University Department of Dermatovenereology, Reference Center for Melanoma and Reference Center for Chronic Wounds of the Ministry of Health and Social Welfare of the Republic of Croatia, Sestre milosrdnice University Hospital, Zagreb, Croatia.

Acta Clinica Croatica
|August 12, 2011
PubMed
Summary

Chemical peels offer enhanced safety and reliability due to new formulations. Physician expertise and patient education are crucial for successful outcomes, covering peel chemistry, skin effects, and post-procedure care.

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Area of Science:

  • Dermatology
  • Cosmetic Procedures

Background:

  • Chemical peels are increasingly popular cosmetic treatments.
  • Advancements in agents, formulas, and methods enhance peel safety and reliability.

Purpose of the Study:

  • To emphasize the critical role of physician knowledge and patient education in chemical peel procedures.
  • To highlight the importance of understanding peel chemistry, skin necrosis levels, indications, contraindications, and potential side effects.
  • To underscore the significance of preoperative and postoperative care in optimizing chemical peel efficacy.

Main Methods:

  • Review of chemical peel agents, formulations, and procedural techniques.
  • Analysis of physician knowledge requirements regarding skin interactions and patient evaluation.
  • Emphasis on patient education for preoperative and postoperative care.

Main Results:

  • Proper physician knowledge and patient education are vital for safe and effective chemical peels.
  • Understanding the chemical structure, necrosis level, indications, contraindications, and side effects is essential.
  • Preoperative and postoperative care significantly impacts treatment outcomes.

Conclusions:

  • Chemical peels require comprehensive physician expertise and thorough patient education.
  • Objective patient evaluation and clear communication of procedure possibilities are necessary.
  • Patient adherence to preoperative and postoperative care is crucial for maximizing chemical peel results.