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Updated: May 30, 2026

Transcranial Direct Current Stimulation and Simultaneous Functional Magnetic Resonance Imaging
Published on: April 27, 2014
Combining transcranial direct current stimulation and neuroimaging: novel insights in understanding neuroplasticity
Anusha Venkatakrishnan1, Marco Sandrini
1Human Cortical Physiology and Stroke Neurorehabilitation Section, National Institute of Neurological Disorders and Stroke, NIH Bldg. 10, Rm. 7D52, Bethesda, MD 20892, USA. venkatakrishna@ninds.nih.gov
Abstract:
In recent years, noninvasive brain stimulation techniques like transcranial direct current stimulation (tDCS) have gained immense popularity owing to their effects on modulating cortical activity and consequently motor and cognitive performance. However, the neurophysiology underlying such neuroplastic changes is less understood. This article critically evaluates the contemporary approach of combined tDCS and neuroimaging as a means to provide novel insights in understanding the neurophysiological and neuroplastic processes modulated by this brain stimulation technique. We end by briefly suggesting further lines of inquiry.

