Optimizing the functionalization process for nanopillar enhanced electrodes with GOx/PPY for glucose detection

In this study, the functionalization process for nanopillar enhanced electrodes (NEEs) using glucose oxidase (GOx) with polypyrrole (PPY) is optimized for the purpose of achieving enhanced sensing performances for these electrodes in glucose detection. Specifically, an optimal roughness factor for the NEEs and an optimal set of electro-polymerization/deposition parameters for their functionalization using GOx/PPY are identified. Results show that NEEs with a roughness factor of about 60 are optimal for enhancing the amperometric current responses and that for such electrodes an electro-functionalization/deposition process at a deposition current of 50 µA cm(-2) and a total charge of 150 mC cm(-2) will give rise to a high sensing performance with a sensitivity as high as 36 µA cm(-2) mM(-1).