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Related Concept Videos

Atomic Force Microscopy01:08

Atomic Force Microscopy

Atomic force microscopy (AFM) is a type of scanning probe microscopy that can analyze topographic details of various specimens like ceramics, glass, polymers, and biological samples. AFM offers over 1000 times more resolution than the optical imaging system. Images generated from AFM are three-dimensional surface profiles, offering an advantage over the flat, two-dimensional images from other imaging techniques.
The AFM Probe
The probe is regarded as the heart of any AFM setup and comprises the...
Atomic Fluorescence Spectroscopy01:29

Atomic Fluorescence Spectroscopy

Atomic fluorescence spectroscopy (AFS) is an analytical technique that involves the electronic transitions of atoms in a flame, furnace, or plasma being excited by electromagnetic (EM) radiation. When these atoms absorb energy, they become excited and subsequently release energy as they return to their original state. This emitted light, or "fluorescence," is observed at a right angle to the incident beam. Both absorption and emission processes transpire at distinct wavelengths, which are...

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Related Experiment Video

Updated: May 30, 2026

Sub-nanometer Resolution Imaging with Amplitude-modulation Atomic Force Microscopy in Liquid
10:25

Sub-nanometer Resolution Imaging with Amplitude-modulation Atomic Force Microscopy in Liquid

Published on: December 20, 2016

Fast image scanning method in liquid-AFM without image distortion.

Inhee Choi1, Younghun Kim, Jong Ho Kim

  • 1School of Chemical and Biological Engineering, Institute of Chemical Processes, Seoul National University, Seoul 151-742, Korea.

Nanotechnology
|August 12, 2011
PubMed
Summary
This summary is machine-generated.

High-speed atomic force microscopy (AFM) enables direct observation of dynamic sample behavior in liquids. This study introduces a variable-controlled fast scanning method to enhance image quality at high speeds up to 200 µm/s.

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Last Updated: May 30, 2026

Sub-nanometer Resolution Imaging with Amplitude-modulation Atomic Force Microscopy in Liquid
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Atomic Force Microscopy Imaging and Force Spectroscopy of Supported Lipid Bilayers
10:15

Atomic Force Microscopy Imaging and Force Spectroscopy of Supported Lipid Bilayers

Published on: July 22, 2015

Area of Science:

  • Nanotechnology
  • Surface Science
  • Biophysics

Background:

  • Atomic Force Microscopy (AFM) is crucial for observing dynamic sample behavior in liquid media.
  • High-speed imaging in AFM requires high resolution for accurate material identification.
  • Existing methods face limitations in maintaining image quality at high scanning rates.

Purpose of the Study:

  • To develop a variable-controlled fast scanning method for AFM in liquid media.
  • To improve image quality and resolution during high-speed AFM imaging.
  • To enable real-time observation of dynamic processes at the nanoscale.

Main Methods:

  • Developed a modified squeeze-drag superposition model for liquid environments.
  • Implemented variable control of loading force and cantilever length.
  • Tested the method on grating samples and elastic biomolecules in various liquids.

Main Results:

  • Achieved non-distorted, high-quality AFM images at scanning speeds up to 200 µm/s.
  • Successfully visualized elastic biomolecules submerged in high kinematic viscosity liquids.
  • Demonstrated the reliability and effectiveness of the method across different liquid media.

Conclusions:

  • The developed variable-controlled fast scanning method significantly enhances AFM imaging speed and quality in liquids.
  • This technique is valuable for nanobiotechnology and studying dynamic processes in biological and material science.
  • The method offers a simple yet effective approach without requiring additional hardware.