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[Selenium and pregnancy].

¹Université Libre de Bruxelles, Laboratoire de Chimie Pharmaceutique Organique, Belgique.

Revue Francaise De Gynecologie Et D'Obstetrique

|January 1, 1990

Summary

Selenium is vital for protecting against oxidative stress. Supplementation during pregnancy is recommended to prevent infant deficiency, especially for premature babies.

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Report on the 3rd International FESTEM Symposium on "Recent advances in trace element research: from experiments to nutritional and clinical applications in humans", Santiago de Compostela, Spain, May 16-19, 2007.

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Area of Science:

Biochemistry
Human Physiology
Nutritional Science

Context:

Selenium is an essential trace element crucial for antioxidant defense.
Pregnancy involves hormonal regulation leading to plasma selenium depletion.
Fetal selenium accumulation occurs in the liver during late pregnancy.

Purpose:

To investigate selenium's role during pregnancy and its impact on infants.
To assess the necessity of selenium supplementation for pregnant and lactating women.

Summary:

Maternal plasma selenium levels decrease during pregnancy due to hormonal changes and increased fetal demand.
While not causing pregnancy complications, maternal selenium deficiency can affect infants, particularly premature ones.
Increased selenium retention via reduced urinary excretion partially meets higher requirements.

Impact:

Infants are vulnerable to selenium deficiency symptoms and exacerbated health issues if born prematurely.
Dietary selenium intake is often marginal, increasing deficiency risk.
Supplementation of 25-50 micrograms of selenium daily is advised for pregnant and lactating women as a food supplement.

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