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Particulate pollutants and racial/ethnic disparity in feto-infant morbidity outcomes
Hamisu M Salihu1, Nafisa Ghaji, Alfred K Mbah
1Department of Obstetrics and Gynecology, College of Medicine, University of South Florida, 2 Tampa General Circle, Tampa, FL 33606, USA. hsalihu@health.usf.edu
Insights
Exposure to air particulate pollutants increases feto-infant morbidity risks, particularly for Black women. These environmental factors exacerbate existing racial disparities in adverse birth outcomes, highlighting a critical area for public health intervention.
Area of Science:
- Environmental Health
- Reproductive Epidemiology
- Perinatal Outcomes
Background:
- Air particulate matter (PM) exposure is a growing public health concern.
- Feto-infant morbidity outcomes are influenced by various environmental factors.
- Racial/ethnic disparities in birth outcomes are well-documented.
Purpose of the Study:
- To assess the association between air particulate pollutants (PM2.5, PM10, coarse PM) and feto-infant morbidity.
- To examine these associations across different racial/ethnic subgroups.
- To investigate the impact of particulate pollutants on widening Black-White disparities in adverse birth outcomes.
Main Methods:
- Retrospective cohort study (2000-2007) using linked Florida databases (hospital discharge, vital statistics, EPA air/meteorological data).
- Exposure assignment via computerized modeling based on proximity to air pollution monitoring sites.
- Primary outcomes: low birth weight, very low birth weight, preterm birth, very preterm birth, small for gestational age (SGA). Adjusted odds ratios approximated relative risks.
Main Results:
- Increased feto-infant morbidity associated with exposure to any of the three particulate pollutants (above median exposure).
- Exposed women showed higher odds for low birth weight, very low birth weight, and preterm birth.
- Black women exposed to particulate pollutants had the highest odds for all morbidity outcomes, especially very low birth weight (AOR=3.32).
Conclusions:
- Environmental particulate pollutants are linked to adverse feto-infant outcomes.
- Black women experience disproportionately higher risks from particulate pollutant exposure.
- Particulate pollutants exacerbate Black-White disparities in adverse fetal outcomes, indicating a need for targeted interventions.
Abstract:
We sought to assess the association between air particulate pollutants and feto-infant morbidity outcomes across racial/ethnic subgroups. This is a retrospective cohort study from 2000 through 2007 based on three linked databases: (1) The Florida Hospital Discharge database; (2) The vital statistics records of singleton live births in Florida; (3) Air pollution and meteorological data from the Environmental Protection Agency. Using computerized mathematical modeling, we assigned exposure values of the air pollutants of interest (PM(2.5), PM(10) and the PM coarse fraction [PM(10) - PM(2.5)]) to mothers over the period of pregnancy based on Euclidean minimum distance from the air pollution monitoring sites. The primary outcomes of interest were: low birth weight, very low birth weight, preterm birth, very preterm birth, and small for gestational age (SGA). We used adjusted odds ratios to approximate relative risks. We observed increased risk for overall feto-infant morbidity outcome in women exposed to any of the three particulate pollutants (values above the median). Exposed women had increased odds for low birth weight, very low birth weight and preterm birth with the greatest risk being that for very low birth weight (AOR = 1.27, 95% CI = 1.08-1.49). Black women exposed to any particulate pollutant had the greatest odds for all the morbidity outcomes, most pronounced for very low birth weight (AOR = 3.32, 95% CI = 2.56-4.30). Environmental particulate pollutants are associated with adverse feto-infant outcomes among exposed women, especially blacks. Black-white disparity in adverse fetal outcomes is widened in the presence of these pollutants, which provide a target for intervention.
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