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Related Concept Videos

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Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
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Prospective Study
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Blind Procedures02:07

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Related Experiment Videos

Checking reference lists to find additional studies for systematic reviews.

Tanya Horsley1, Orvie Dingwall, Margaret Sampson

  • 1Centre for Learning in Practice, Royal College of Physicians and Surgeons of Canada, 774 Echo Drive, Ottawa, Ontario, Canada, K1S5N8.

The Cochrane Database of Systematic Reviews
|August 12, 2011
PubMed
Summary
This summary is machine-generated.

Checking reference lists can help find more studies for systematic reviews, though evidence comes from studies with high risk of bias. This method is useful when other searches are difficult.

Related Experiment Videos

Area of Science:

  • Information Science
  • Medical Research Methodology

Background:

  • Checking reference lists is a common recommendation for systematic reviews.
  • Its effectiveness as a supplementary search method has not been systematically reviewed.

Purpose of the Study:

  • To evaluate the effectiveness of checking reference lists for identifying additional relevant studies in systematic reviews.
  • To define effectiveness as the proportion of relevant studies found solely through reference list checking.

Main Methods:

  • Searched Cochrane Library, LISA, and MEDLINE databases.
  • Contacted systematic review experts and examined article reference lists.
  • Included studies of any design evaluating reference list checking for systematic reviews.

Main Results:

  • Twelve studies were included, but designs had high risk of bias, limiting interpretability.
  • The additional yield of relevant studies from reference list checking ranged from 2.5% to 42.7%.
  • Limited data on publication types; no cost-effectiveness data were reported.

Conclusions:

  • Some evidence supports using reference list checking to find studies for systematic reviews.
  • The evidence is based on weak study designs.
  • Checking reference lists is prudent when database and handsearching are insufficient, but identifying such situations is key.