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Related Experiment Videos

Risks of hepatitis B for travellers.

R Steffen1

  • 1Division of Epidemiology and Prevention of Communicable Diseases, Institute of Social and Preventive Medicine, Zurich, Switzerland.

Vaccine
|March 1, 1990
PubMed
Summary

Hepatitis B virus (HBV) infection risk is higher for those working long-term in developing countries compared to vacationers. Vaccination is recommended for prolonged stays, especially for healthcare workers, to prevent HBV transmission.

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Area of Science:

  • Travel Medicine
  • Infectious Diseases
  • Vaccinology

Background:

  • Travelers to developing countries face a risk of symptomatic hepatitis B virus (HBV) infection.
  • Studies indicate a prevalence of approximately 1 in 2500 travelers developing HBV infection post-travel.
  • Individuals working long-term in these regions exhibit higher seroconversion rates than short-term vacationers.

Purpose of the Study:

  • To assess the risk of hepatitis B virus infection in travelers to developing countries.
  • To determine the necessity and target groups for hepatitis B vaccination in travelers.
  • To provide guidance on HBV immunization strategies for different travel scenarios.

Main Methods:

  • Retrospective analysis of traveler health data.
  • Follow-up studies on individuals returning from developing countries.
  • Comparison of infection rates between long-term residents/workers and vacationers.

Main Results:

  • A significant risk of symptomatic HBV infection exists for travelers to developing countries.
  • Long-term residents and workers are more prone to HBV seroconversion than tourists.
  • Vacationers generally have a low risk unless engaging in high-risk behaviors.

Conclusions:

  • Hepatitis B vaccination is strongly indicated for individuals residing long-term in developing countries.
  • Specific groups like medical personnel and missionaries require vaccination due to close population contact.
  • Routine HBV immunization is typically not necessary for short-term vacationers without hygiene compromise.

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