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[Generalized tendomyopathy. II: Pathogenesis and therapy]
1Rheumatologische Universitätsklinik, Felix Platter-Spital, Basel, Schweiz.
Zeitschrift Fur Rheumatologie
|January 1, 1990
Summary
Generalized tendomyopathy (GTM), or fibromyalgia, involves complex pathogenesis with psychological factors dominating as the condition spreads. Early recognition and tailored treatments, including antidepressants and psychotherapy, are crucial for managing this often debilitating condition.
Area of Science:
- Rheumatology
- Psychosomatic Medicine
Context:
- Generalized tendomyopathy (GTM), also known as fibromyalgia, presents diagnostic challenges, particularly primary forms.
- Secondary GTM often co-occurs with conditions like rheumatoid arthritis.
Purpose:
- To elucidate the multifactorial pathogenesis of generalized tendomyopathy (GTM).
- To explore the transition from localized symptoms to generalized GTM, emphasizing psychological and psychosocial factors.
- To outline effective therapeutic strategies and highlight the importance of early diagnosis.
Summary:
- GTM pathogenesis involves local spinal/joint issues initially, progressing to psychological and psychosocial factors in generalized stages.
- Effective GTM management requires physician empathy, causal factor elimination, antidepressants, neuroleptics, physiotherapy, and psychotherapy.
- While GTM can be treatment-resistant, it may naturally remit post-age 60.
Impact:
- Early GTM recognition is vital to initiate prompt, appropriate treatment and prevent misdiagnoses.
- Proper diagnosis and management of GTM can avert consequences like unnecessary surgeries and premature disability.
- Understanding GTM's complex etiology aids in developing more targeted and effective treatment protocols.