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[Basilingual xanthoma].

Daniel Pérez-Plasencia¹, Gloria Guerra-Jiménez, Társila Montenegro-Dámaso

¹Servicio de ORL, Complejo Hospitalario Universitario Insular Materno Infantil, Las Palmas de Gran Canaria, España.

Acta Otorrinolaringologica Espanola

|August 13, 2011

Summary

Xanthomas, rare tumors of lipid-laden cells, can affect the aerodigestive tract. This case highlights successful laser resection for epiglottic xanthoma causing dysphagia.

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Area of Science:

Otorhinolaryngology (ENT)
Dermatology
Pathology

Background:

Xanthomas are benign, slow-growing tumors characterized by lipid-laden histiocytes.
They present as either dyslipidemic or normolipidemic forms, with or without altered lipid levels.
Xanthoma involvement of the upper aerodigestive tract is exceptionally rare.

Observation:

A case of dyslipidemic xanthomatosis affecting the epiglottis and base of the tongue is presented.
The patient experienced symptoms of oropharyngeal foreign body sensation and dysphagia.
These symptoms were attributed to the xanthoma's location and size.

Findings:

Histopathological examination confirmed xanthoma composed of cholesteryl ester and triglyceride-laden histiocytes.
The dyslipidemic nature of the xanthoma was correlated with the patient's lipid profile.
The tumor's presence in the epiglottis and basilingual area was the primary cause of the patient's symptoms.

Implications:

This case underscores the importance of considering xanthoma in the differential diagnosis of oropharyngeal symptoms, even in rare locations.
Surgical intervention, such as laser resection, can be an effective treatment for symptomatic aerodigestive tract xanthomas.
Further research into the pathogenesis and management of xanthomas in this specific anatomical region may be warranted.