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Updated: May 30, 2026

Human Primary Trophoblast Cell Culture Model to Study the Protective Effects of Melatonin Against Hypoxia/reoxygenation-induced Disruption
Published on: July 30, 2016
Contribution of myo-inositol and melatonin to human reproduction
G Carlomagno1, M Nordio, T T Chiu
1AGUNCO, Obstetrics and Gynaecology Center, Via G. Cassiani, 15, 00155 Rome, Italy. gianfranco.carlomagno@gmail.com
Abstract:
Diet is a critical factor for the development of both embryo and fetus, as well as maternal health. In particular, two natural molecules have been shown to exert beneficial effects on fertility, pregnancy wellness and embryo development: myo-inositol and melatonin, whose requirements increase during pregnancy. In the present review, we summarize the most important functions of melatonin and myo-inositol on male and female reproductive systems (oocyte quality and development, sperm quality), on the maintenance of a physiological pregnancy and on embryo development.
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