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The new World Health Organization Classification of Central Nervous System Tumors: what can the neuroradiologist
A G Osborn1, K L Salzman, M M Thurnher
1University of Utah School of Medicine, Salt Lake City, UT 84132, USA. Anne.Osborn@hsc.utah.edu
Abstract:
The WHO Classification of Tumors of the Central Nervous System has become the worldwide standard for classifying and grading brain neoplasms. The most recent edition (WHO 2007) introduced a number of significant changes that include both additions and redefinitions or clarifications of existing entities. Eight new neoplasms and 4 new variants were introduced. This article reviews these entities, summarizing both their histology and imaging appearance. Now with more than 3 years of clinical experience following publication of the newest revision, we also ask, "What can the neuroradiologist really say?" Are there imaging findings that could suggest the preoperative diagnosis of a new tumor entity or variant?
