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Coffee consumption and serum lipids: a randomized, crossover clinical trial
P C Rosmarin1, W B Applegate, G W Somes
1Department of Medicine, University of Tennessee, Memphis 38163.
Purpose:
The purpose of this study was to determine the effect of consuming three or more cups of filter-brewed coffee per day on levels of serum lipids.
Subjects And Methods:
A prospective, randomized crossover clinical trial was performed. Twenty-one healthy white male subjects completed the trial, and consumed an average of 3.6 cups of coffee a day. Data were evaluated by analysis of variance for repeated measures and t-test for paired means.
Results:
No effect of coffee consumption on serum total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, or apolipoprotein B was found. Diet, creamer use, and cigarette use as well as group assignment and time factors were controlled for in the analysis.
Conclusion:
We found no effect of moderate consumption of filter-brewed coffee on serum levels of atherogenic lipids. This study supports previous work that filtered coffee has no adverse effect on serum lipids. This has far-reaching implications given the widespread use of coffee and the current concern over coronary risk factors.