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Macular hole in Behçet's disease
Hassan Al-Dhibi1, Marwan Abouammoh, Essam Al-Harthi
1Uveitis Division, College of Medicine, King Saud University, Riyadh, Saudi Arabia. hdhibi@yahoo.com
Indian Journal of Ophthalmology
|August 13, 2011
Summary
Macular holes (MH) in Behcet's disease (BD) patients cause vision loss. Surgery for MH in BD did not improve visual acuity, likely due to macular ischemia and inflammation.
Area of Science:
- Ophthalmology
- Rheumatology
- Medical Research
Background:
- Behcet's disease (BD) is a multisystem inflammatory disorder.
- Macular holes (MH) can occur in patients with BD, leading to visual impairment.
Purpose of the Study:
- To determine the clinical features, prevalence, and visual prognosis of MH in BD patients.
- To evaluate the role and effectiveness of surgical intervention for MH in BD.
Main Methods:
- Retrospective study of BD patients with MH from 1998 to 2008.
- Analysis of clinical data, optical coherence tomography (OCT), and fluorescein angiography (FA).
- Assessment of visual acuity (VA) before and after treatment, including surgery.
Main Results:
- MH prevalence was 7% in BD patients (17 patients, 21 eyes).
- Macular ischemia was present in 76% of cases; surgical intervention showed no visual improvement.
- Human leukocyte antigen (HLA) B51 association was noted in most patients.
Conclusions:
- MH in BD can cause significant visual disability.
- Surgical intervention for MH in BD appears ineffective, likely due to underlying macular ischemia and ocular inflammation.
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