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Fungal Phylum Microsporidia

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Microbiome of the Eye

The human eye has a specialized microbiota that reflects its unique anatomical and immunological environment. This low-biomass microbial community predominantly colonizes the conjunctiva and eyelid margins, playing a vital role in ocular surface homeostasis and defense. Despite its proximity to the richly colonized facial skin, the ocular surface maintains a distinct microbial profile due to continuous mechanical and biochemical defense mechanisms.The conjunctival surface hosts fewer microbial...
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Updated: May 30, 2026

Corneal Sensitivity Testing Procedure for Ophthalmologic and Optometric Patients
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Corneal Sensitivity Testing Procedure for Ophthalmologic and Optometric Patients

Published on: August 2, 2024

Mycotic corneal ulcers in upper Assam.

Reema Nath1, Syamanta Baruah, Lahari Saikia

  • 1Department of Microbiology, Assam Medical College and Hospital, Dibrugarh, India. reema_44@rediffmail.com

Indian Journal of Ophthalmology
|August 13, 2011
PubMed
Summary

Mycotic keratitis, a fungal eye infection, is frequently caused by ocular trauma in Assam, India. Fusarium solani is the most common fungal species identified, particularly affecting individuals in rural areas.

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Last Updated: May 30, 2026

Corneal Sensitivity Testing Procedure for Ophthalmologic and Optometric Patients
04:00

Corneal Sensitivity Testing Procedure for Ophthalmologic and Optometric Patients

Published on: August 2, 2024

Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Medical Mycology

Background:

  • Mycotic keratitis poses a significant threat to vision, especially in agricultural regions.
  • Understanding the epidemiology and risk factors is crucial for effective prevention and treatment.

Purpose of the Study:

  • To investigate the risk factors and epidemiological characteristics of mycotic keratitis in Upper Assam.
  • To identify common fungal species causing keratitis in the region.

Main Methods:

  • A prospective hospital-based study enrolled 310 corneal ulcer cases over two years.
  • Clinical examination, slit-lamp biomicroscopy, and laboratory analysis (KOH smears, fungal cultures) were performed.
  • Data on demographics and risk factors were collected using questionnaires.

Main Results:

  • Fungal etiology was confirmed in 60.6% of cases, predominantly in males (67.6%) aged 41-50.
  • Corneal injury was the leading predisposing factor (74.5%), followed by diabetes and blocked nasolacrimal duct (11.1% each).
  • Fusarium solani (25%) was the most prevalent isolate, followed by Aspergillus, Curvularia, and Penicillium species.

Conclusions:

  • Ocular trauma is the primary cause of fungal corneal ulcers in Assam.
  • Fusarium solani is the most common causative agent, with rural populations and tea garden workers being particularly vulnerable.