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Updated: May 30, 2026

14:49
Clinical Protocol of Producing Adipose Tissue-Derived Stromal Vascular Fraction for Potential Cartilage Regeneration
Published on: September 29, 2018
A 15-year-old male with persistent knee pain
1Emergency Department, St. Mary Medical Center, Long Beach, California 90813, USA. ssshea01@hotmail.com
Advanced Emergency Nursing Journal
|August 13, 2011
Summary
Most emergency department visits for extremity pain in children are minor. Persistent or nighttime pain warrants investigation for serious underlying causes, requiring thorough initial evaluation.
Area of Science:
- Pediatric Emergency Medicine
- Musculoskeletal Disorders
- Clinical Diagnosis
Background:
- Extremity pain is a common emergency department (ED) presentation in children and adolescents.
- Most cases involve minor injuries or musculoskeletal issues.
- However, persistent or nocturnal pain necessitates further investigation.
Observation:
- A significant minority of pediatric extremity pain cases may indicate serious underlying conditions.
- Thorough patient history and initial screening are crucial for identifying at-risk patients.
- Reviewing prior medical care aids in differential diagnosis.
Findings:
- Persistent extremity pain or pain disrupting sleep in pediatric patients is a red flag.
- Serious clinical etiologies must be considered in the differential diagnosis.
- Comprehensive initial assessment is vital for accurate diagnosis and management.
Implications:
- Early identification of serious causes of pediatric extremity pain can prevent delayed treatment.
- Healthcare providers should maintain a high index of suspicion for non-minor etiologies.
- Effective ED screening protocols can improve patient outcomes and resource allocation.
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