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Updated: May 30, 2026

Protocol for the Synthesis of Ortho-trifluoromethoxylated Aniline Derivatives
Published on: January 19, 2016
2-(4-Chloro-phen-yl)-2-oxoethyl 2,4-di-fluoro-benzoate
Abstract:
The asymmetric unit of title compound, C(15)H(9)ClF(2)O(3), consists of two crystallographically independent mol-ecules. The dihedral angle between the two terminal benzene rings in one mol-ecule is 7.92 (14)°, while that in the other mol-ecule is 73.50 (16)°. In the crystal, mol-ecules are stacked into columns along the b axis by inter-molecular C-H⋯O hydrogen bonds. A π-π inter-action with a centroid-to-centroid distance of 3.747 (2) Å further stabilizes the crystal structure.
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