Related Experiment Video
Updated: May 30, 2026

Preparation of Enantiopure Non-Activated Aziridines and Synthesis of Biemamide B, D, and epiallo-Isomuscarine
Published on: June 13, 2022
(E)-N'-(2-Chloro-5-nitro-benzyl-idene)-3-meth-oxy-benzohydrazide monohydrate
Abstract:
In the hydrazone mol-ecule of the title compound, C(15)H(12)ClN(3)O(4)·H(2)O, the two benzene rings form a dihedral angle of 3.6 (1)°. In the crystal structure, the solvent water mol-ecules are involved in the formation of inter-molecular N-H⋯O and O-H⋯N hydrogen bonds, which link the mol-ecules into double ribbons extending along the b axis. Inter-molecular π-π inter-actions between the aromatic rings [centroid-centroid distances = 3.712 (3) and 3.672 (3) Å] link these ribbons further into layers parallel to the ab plane.
Related Concept Videos
Diazonium Group Substitution: –OH and –H
Formation of Halohydrin from Alkenes
Preparation of Epoxides
Epoxides result from alkene oxidation, which can be achieved by a) air, b) peroxy acids, c) hypochlorous acids, and d) halohydrin cyclization.
Epoxidation with Peroxy Acids
Epoxidation of alkenes via oxidation with peroxy acids involves the conversion of a carbon–carbon double bond to an epoxide using the oxidizing agent meta-chloroperoxybenzoic acid, commonly known as MCPBA. Since the O–O bond of peroxy acids is very weak, the addition of electrophilic oxygen of peroxy acids to...
Nitrosation of Enols
Reactivity of Enols
Carboxylic Acids to Methylesters: Alkylation using Diazomethane

