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Decay of the ampicillin-induced lysis process in amino acid-deprived Escherichia coli
W Kusser1, A G Pisabarro, M A De Pedro
1Department of Biochemistry and Microbiology, University of Victoria, British Columbia, Canada.
Antimicrobial Agents and Chemotherapy
|January 1, 1990
Abstract:
The ability to induce the ampicillin-mediated lysis of amino acid-deprived Escherichia coli by relaxing the stringent response decreased progressively during the course of amino acid deprivation, apparently because of a time-dependent decay in a key lysis event. The decay of this labile activity was not apparent when ampicillin treatment was initiated early and maintained continuously throughout the amino acid starvation period.