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Updated: May 30, 2026

Synthesis of pH Dependent Pyrazole, Imidazole, and Isoindolone Dipyrrinone Fluorophores using a Claisen-Schmidt Condensation Approach
Published on: June 10, 2021
3-Ethyl-5-(4-meth-oxy-phen-oxy)-2-(pyridin-4-yl)-3H-imidazo[4,5-b]pyridine
Abstract:
In the title compound, C(20)H(18)N(4)O(2), the imidazopyridine fused ring system is almost perpendicular to the benzene ring [dihedral angle = 87.6 (5)°]. The pyridine ring makes a dihedral angle of 35.5 (5)° with the mean plane of the imidazopyridine fragment. The crystal structure is stabilized by an aromatic π-π stacking inter-action between the phenyl rings of neighbouring mol-ecules [centroid-centroid distance = 3.772 (2) Å, inter-planar distance = 3.546 (2) Å and slippage = 1.286 (2) Å].
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