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Updated: May 30, 2026

Protocol for the Synthesis of Ortho-trifluoromethoxylated Aniline Derivatives
Published on: January 19, 2016
4-(4-Meth-oxy-benzene-sulfonamido)-benzoic acid
Abstract:
The asymmetric unit of the title compound, C(14)H(13)NO(5)S, contains two independent mol-ecules in which the dihedral angles between the aromatic rings are 83.45 (11) and 86.65 (9)°. In the crystal, the independent mol-ecules are connected by N-H⋯O and O-H⋯O hydrogen bonds, forming a double-chain structure along [401]. A weak π-π stacking inter-action with a centroid-centroid distance of 3.7509 (13) Å and C-H⋯O hydrogen bonds are also observed.
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