Related Experiment Video
Updated: May 30, 2026

10:26
Whole Genome Sequencing for Rapid Characterization of Rabies Virus Using Nanopore Technology
Published on: August 18, 2023
Pseudorabies virus in wild swine: a global perspective
T Müller1, E C Hahn, F Tottewitz
1Institute of Epidemiology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Seestrasse 55, 16868 Wusterhausen, Germany. Thomas.Mueller@fli.bund.de
Archives of Virology
|August 13, 2011
Summary
Pseudorabies virus (PrV) infections are increasingly detected in wild swine globally. Further research is crucial to understand PrV
Area of Science:
- Veterinary Virology
- Wildlife Epidemiology
- Disease Ecology
Background:
- Suid herpesvirus 1 (SuHV1), also known as pseudorabies virus (PrV), causes Aujeszky's disease (AD) in swine, leading to significant economic losses.
- While domestic pigs are the primary hosts, PrV infects various mammals, and its prevalence in wild swine populations is increasingly recognized.
Purpose of the Study:
- To provide a global overview of PrV infections in wild swine populations.
- To assess the molecular characteristics, infection patterns, and risks associated with PrV in wild swine.
- To identify potential risk-mitigation strategies and research needs.
Main Methods:
- Comprehensive review of existing literature on PrV in wild swine.
- Analysis of global occurrence data and molecular characterization studies.
- Evaluation of spillover risks to domestic pigs and control measures.
Main Results:
- PrV infections are more widespread in global wild swine populations than previously understood.
- Molecular data reveals variations in PrV strains circulating in wild populations.
- Evidence suggests a potential for PrV transmission from wild to domestic swine.
Conclusions:
- Understanding PrV dynamics in wild swine is critical for preventing disease spread to domestic herds.
- Further research is needed to refine risk assessments and develop effective mitigation strategies.
- Global surveillance and coordinated control efforts are essential for managing PrV in both wild and domestic swine.
Related Concept Videos
Rabies
Rabies is a lethal zoonotic disease caused by a single-stranded, negative-sense RNA virus of the Lyssavirus genus, within the family Rhabdoviridae. Its primary mode of transmission to humans is through bites or saliva-contaminated scratches from infected mammals such as dogs, bats, raccoons, or foxes. Transmission can also occur if infectious saliva contacts abraded skin or intact mucous membranes, including the conjunctiva.Viral Entry and Early ReplicationOnce introduced at the bite or scratch...
Viral Recombination
Cells are sometimes infected by more than one virus at once. When two viruses disassemble to expose their genomes for replication in the same cell, similar regions of their genomes can pair together and exchange sequences in a process called recombination. Alternatively, viruses with segmented genomes can swap segments in a process called reassortment.

