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Ligand-Mediated Nucleation and Growth of Palladium Metal Nanoparticles
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Accelerating palladium-catalyzed C-F bond formation: use of a microflow packed-bed reactor

Timothy Noël1, Thomas J Maimone, Stephen L Buchwald

  • 1Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA.

Angewandte Chemie (International Ed. in English)
|August 13, 2011
PubMed
Abstract

No abstract available in PubMed .

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Fast reactions occurring in times shorter than the time needed to mix reactants pose a unique challenge for investigation. In a liquid-phase continuous-flow system, reactants A and B are swiftly pushed into the mixing chamber, where mixing occurs within 1 ms. The reaction mixture then flows through an observation tube, and one measures light absorption to determine species concentrations at various points of the tube. This method is most appropriate when relatively large volumes of reactants...
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