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07:21
Processing of Bronchoalveolar Lavage Fluid and Matched Blood for Alveolar Macrophage and CD4+ T-cell Immunophenotyping and HIV Reservoir Assessment
Published on: June 23, 2019
[Tuberculosis in HIV/AIDS patients]
1Department of Pulmonary Medicine, Tokyo Metropolitan Tama Medical Center.
Nihon Rinsho. Japanese Journal of Clinical Medicine
|August 16, 2011
Summary
In Japan, 0.37% of active tuberculosis (TB) patients are HIV-positive. Guidelines recommend immediate TB treatment for co-infected individuals and timely antiretroviral therapy (ART) initiation.
Area of Science:
- Infectious Diseases
- Public Health
- Epidemiology
Context:
- Review of recent literature and guidelines on Tuberculosis/Human Immunodeficiency Virus (TB/HIV) co-infection.
- Japanese research indicates 0.37% of active TB patients are HIV-positive.
- Over 60% of TB/HIV co-infected patients receive simultaneous diagnosis.
Purpose:
- To summarize current guidelines for managing TB/HIV co-infection.
- To highlight key epidemiological findings from Japanese research.
- To provide recommendations for integrated TB and HIV care.
Summary:
- Immediate initiation of TB treatment is crucial for HIV-infected patients with active TB.
- Antiretroviral therapy (ART) should be started within 2-8 weeks of TB treatment, based on CD4 count.
- Testing for Latent Tuberculosis Infection (LTBI) is recommended for all HIV-infected individuals.
- The World Health Organization's (WHO) three 'I's strategy can aid in preventing active TB disease.
Impact:
- Informed clinical decision-making for TB/HIV co-infected patients.
- Improved patient outcomes through timely and integrated treatment.
- Enhanced public health strategies for TB and HIV prevention and control.
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