[Renal cystic diseases as a ciliopathy]

Takahiko Yokoyama1

  • 1Division of Developmental Biology, Department of Anatomy, Kyoto Prefectural University of Medicine.

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Proximal Convoluted Tubule (PCT):
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Renal calculi, commonly termed kidney stones, are crystalline solid masses that form in the kidneys but can occur at any point within the urinary system, encompassing the kidneys, ureters, bladder, and urethra.The pathophysiology of renal stones involves several key factors: supersaturation of the urine with stone-forming constituents, changes in urine pH, a decrease in urine volume, and the presence of substances that promote or inhibit stone formation.Supersaturation of Urine: This is the...