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Updated: May 30, 2026

Ultrasound Assessment of Endothelial-Dependent Flow-Mediated Vasodilation of the Brachial Artery in Clinical Research
Published on: October 22, 2014
[Ankle-brachial index assessed in a Mexican population with vascular risk. The INDAGA study]
Carlos Cantú-Brito1, Erwin Chiquete, Manuel Duarte-Vega
1Departamento de Neurología y Psiquiatría. Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Distrito Federal, México. carloscantu_brito@hotmail.com
Objective:
to know the peripheral arterial disease (PAD) prevalence and its determinants in a nationwide survey in Mexican population.
Methods:
baseline ankle brachial index (ABI) measured by Doppler was performed in patients at high vascular risk for PAD. ABI between 1 and 1.3 was regarded as normal. ABI ≤ 0.9 (a low ABI) was considered to be an indicator of PAD. ABI > 1.3 (a high ABI) was also considered abnormal, as an indirect index of artery calcification and stiffness.
Results:
a total of 5 101 patients were evaluated: 1,212 patients (23.8 %) had ABI ≤ 0.9, and 431 (8.4 %) > 1.3 (including 1 % with incompressible vessels). ABI ≤ 0.9 was associated with age, arterial hypertension, diabetes, current smoking, dyslipidemia and previous vascular events. On the other hand, ABI > 1.3 was associated with male gender, diabetes, previous smoking habit and history of vascular events. A high proportion of patients (62.5 %) with established PAD, identified by a low ABI (≤ 0.9) were asymptomatic or with minimum symptoms at the time of their assessment.
Conclusion:
a significant prevalence of abnormal ABI was identified. ABI measurement by Doppler can help to identify patients who need intense secondary prevention and more aggressive treatment of vascular risk factors.
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