Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: May 30, 2026

Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations
14:58

Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations

Published on: October 20, 2017

Gamma knife surgery for brainstem arteriovenous malformations.

Chun-Po Yen1, Ladislau Steiner

  • 1Lars Leksell Center for Gamma Surgery, Department of Neurological Surgery, University of Virginia, Charlottesville, Virginia, USA. cy4f@virginia.edu

World Neurosurgery
|August 16, 2011
PubMed
Summary

Gamma Knife surgery (GKS) offers a viable treatment for brainstem arteriovenous malformations (AVMs), achieving a 59% obliteration rate with a low risk of permanent neurological deficits. This makes GKS a reasonable option for these challenging vascular lesions.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Comparing those Most Satisfied Versus Least Satisfied Following Surgery for Cervical Spondylotic Myelopathy: Are there Differences in Baseline Characteristics?

Spine·2026
Same author

Predictors of long-term myelopathy relief in patients with moderate to severe cervical spondylotic myelopathy following surgery: a Spine CORe™ analysis of QOD data.

Neurosurgical focus·2026
Same author

What determines patient satisfaction after surgery for grade 2 lumbar spondylolisthesis? A Spine CORe™ analysis of QOD data.

Neurosurgical focus·2026
Same author

Is patient satisfaction static at 5 years after surgery for cervical spondylotic myelopathy? A Spine CORe™ analysis of QOD data.

Neurosurgical focus·2026
Same author

What is the average time frame of clinically meaningful improvement in surgical decompression for cervical spondylotic myelopathy? A Spine CORe™ analysis of QOD data: 5-year follow-up.

Neurosurgical focus·2026
Same author

What are the predictors of prolonged length of stay following single-stage lumbar fusion for grade 2 spondylolisthesis? A Spine CORe™ analysis of QOD data.

Neurosurgical focus·2026

Area of Science:

  • Neurosurgery
  • Radiosurgery
  • Vascular Neurology

Background:

  • Brainstem arteriovenous malformations (AVMs) present significant management challenges due to their critical location.
  • Surgical intervention for brainstem AVMs is associated with poor clinical outcomes.
  • Gamma Knife surgery (GKS) has emerged as a potential therapeutic option for these complex lesions.

Purpose of the Study:

  • To evaluate the long-term imaging and clinical outcomes of patients with brainstem AVMs treated with Gamma Knife surgery (GKS).

Main Methods:

  • Retrospective analysis of 85 patients with brainstem AVMs treated with GKS between 1989 and 2007.
  • Nidus locations included the midbrain, pons, and medulla oblongata, with volumes ranging from 0.1-8.9 mL.
  • Follow-up included imaging and clinical assessments, with repeat GKS performed for residual AVMs.

More Related Videos

Minimally Invasive Thumb-sized Pterional Craniotomy for Surgical Clip Ligation of Unruptured Anterior Circulation Aneurysms
11:58

Minimally Invasive Thumb-sized Pterional Craniotomy for Surgical Clip Ligation of Unruptured Anterior Circulation Aneurysms

Published on: August 11, 2015

Permanent Cerebral Vessel Occlusion via Double Ligature and Transection
08:22

Permanent Cerebral Vessel Occlusion via Double Ligature and Transection

Published on: July 21, 2013

Related Experiment Videos

Last Updated: May 30, 2026

Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations
14:58

Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations

Published on: October 20, 2017

Minimally Invasive Thumb-sized Pterional Craniotomy for Surgical Clip Ligation of Unruptured Anterior Circulation Aneurysms
11:58

Minimally Invasive Thumb-sized Pterional Craniotomy for Surgical Clip Ligation of Unruptured Anterior Circulation Aneurysms

Published on: August 11, 2015

Permanent Cerebral Vessel Occlusion via Double Ligature and Transection
08:22

Permanent Cerebral Vessel Occlusion via Double Ligature and Transection

Published on: July 21, 2013

Main Results:

  • Angiographic obliteration was achieved in 58.8% of patients, with subtotal obliteration in 4.7%.
  • A small nidus volume and higher prescription dose correlated with increased obliteration rates.
  • Radiation-induced changes occurred in 40% of patients, with 6% experiencing permanent neurologic deficits.

Conclusions:

  • Gamma Knife surgery (GKS) demonstrates a 59% nidus obliteration rate for brainstem AVMs.
  • The procedure resulted in a 6% rate of permanent neurologic deficits, making it a reasonable management option.
  • GKS offers a valuable alternative for managing difficult-to-treat brainstem AVMs.