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Updated: May 30, 2026
05:11
Treatment of Middle-segment Pancreatic Benign Tumor Using Laparoscopic Central Pancreatectomy with End-to-end Pancreatic Duct Reconstruction
Published on: January 2, 2026
Primary retroperitoneal acinar cell cystadenoma.
Anna Pesci1, Paola Castelli, Enrico Facci
1Department of Pathology, S. Cuore Don Calabria Negrar 37024, Italy. anna.pesci@sacrocuore.it
Human Pathology
|August 16, 2011
Summary
This report details a rare primary retroperitoneal acinar cell cystadenoma, mimicking pancreatic lesions. This benign tumor, identified by trypsin markers, aids in diagnosing retroperitoneal cystic masses.
Area of Science:
- Gastroenterology
- Surgical Pathology
- Oncology
Background:
- Pancreatic acinar cell cystadenoma is a rare, benign neoplasm.
- Characterized by acinar cell differentiation and pancreatic exocrine enzyme production.
- Typically lacks cellular atypia.
Observation:
- A 55-year-old woman presented with a large retroperitoneal cystic mass.
- Initial diagnoses included mucinous cystic neoplasm and cystic lymphangioma.
- The mass was surgically resected and found to be unconnected to any organ.
Findings:
- Morphological and immunophenotypical analysis revealed a primary retroperitoneal acinar cell cystadenoma.
- Immunohistochemistry confirmed acinar differentiation and detected trypsin, a pancreatic exocrine enzyme.
- Absence of cellular atypia was noted, consistent with a benign lesion.
Implications:
- This case represents a hitherto unreported primary retroperitoneal acinar cell cystadenoma.
- The distinct features are crucial for differentiating it from other retroperitoneal cystic lesions.
- Highlights the importance of comprehensive histopathological and immunohistochemical evaluation in diagnosing rare tumors.
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