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Updated: May 30, 2026
Robot-assisted Total Mesorectal Excision and Lateral Pelvic Lymph Node Dissection for Locally Advanced Middle-low Rectal Cancer
Published on: February 12, 2022
Nonoperative approach to locally advanced rectal cancer after neoadjuvant combined modality therapy: challenges and
Katherine N Fischkoff1, Jeannine A Ruby, José G Guillem
1Department of Surgery, Colorectal Service, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
Abstract:
This review contains a surgical perspective on the evolution of the nonoperative approach to patients with locally advanced rectal cancer who have a clinical complete response after neoadjuvant combined modality therapy, including accuracy of pathologic complete response identification, the timing between neoadjuvant combined modality therapy and assessment of response, the extent of long-term follow-up, and the likelihood of surgical salvage after an initial nonoperative approach.
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