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Parallel evolution of Bacillus thuringiensis toxin resistance in lepidoptera
Simon W Baxter1, Francisco R Badenes-Pérez, Anna Morrison
1Department of Zoology, University of Cambridge, Cambridge CB2 3EJ, United Kingdom. swb29@cam.ac.uk
None:
Despite the prominent and worldwide use of Bacillus thuringiensis (Bt) insecticidal toxins in agriculture, knowledge of the mechanism by which they kill pests remains incomplete. Here we report genetic mapping of a membrane transporter (ABCC2) to a locus controlling Bt Cry1Ac toxin resistance in two lepidopterans, implying that this protein plays a critical role in Bt function.
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