Percutaneous coronary intervention in elderly patients: is it beneficial?
1Department of Internal Medicine, University of Arizona College of Medicine, Tucson, AZ 85724, USA. smadhan13@gmail.com
Insights
Elderly patients with acute coronary syndrome often benefit from percutaneous coronary intervention (PCI). This review supports PCI for older adults, challenging the "treatment-risk" paradox that limits revascularization in this population.
Area of Science:
- Cardiology
- Geriatric Medicine
Background:
- Cardiovascular disease is a leading cause of death in individuals aged 65 and older.
- Acute coronary syndrome (ACS) significantly contributes to mortality in the elderly population.
- Percutaneous coronary intervention (PCI) is a standard treatment for ACS and symptomatic coronary artery disease.
Purpose of the Study:
- To review clinical trials and evidence supporting PCI in elderly patients.
- To address the underutilization of revascularization in older adults with ACS.
- To challenge the "treatment-risk" paradox that may deny elderly patients beneficial treatments.
Main Methods:
- Review of existing clinical trials and scientific literature.
- Analysis of evidence regarding PCI outcomes in elderly populations.
- Examination of factors contributing to the avoidance of PCI in older patients.
Main Results:
- Evidence suggests elderly patients can benefit from PCI for ACS.
- Age alone should not be a contraindication for revascularization.
- Studies indicate a potential benefit of PCI in reducing morbidity and mortality in this demographic.
Conclusions:
- Percutaneous coronary intervention is a viable and beneficial treatment option for elderly patients with acute coronary syndrome.
- Clinical decisions regarding PCI in older adults should be based on comprehensive risk-benefit assessments, not solely on age.
- Further research and clinical practice should aim to reduce disparities in PCI utilization among elderly patients.
Abstract:
Persons aged 65 years or older, often referred to as the elderly, are a rapidly increasing population in the United States. Cardiovascular disease is the most common cause of morbidity and death in this age group, and acute coronary syndrome accounts for a significant proportion of the deaths. Percutaneous coronary intervention is a well-established treatment for acute coronary syndrome and symptomatic coronary artery disease. However, community studies have shown that elderly patients are less likely to undergo revascularization, perhaps due to a "treatment-risk" paradox: elderly patients-at higher risk of morbidity and death from acute coronary syndrome-are denied revascularization even though they are likely to benefit from it. Age alone is one of the many reasons why percutaneous coronary intervention is avoided in elderly patients. This review examines past clinical trials and the existing evidence that supports performing percutaneous coronary intervention in elderly patients.
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