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Papillary glioneuronal tumor: unexplored entity.

S Lavrnic¹, M Macvanski, D Ristic-Balos

¹Clinical Center of Serbia, Center for Radiology and Magnetic Resonance Imaging, Belgrade, Serbia.

Journal of Neurological Surgery. Part A, Central European Neurosurgery

|August 16, 2011

Summary

Papillary glioneuronal tumors are rare brain neoplasms. This review highlights their clinicopathological and advanced MRI features, focusing on atypical cases.

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Area of Science:

Neuro-oncology
Neuroradiology
Pathology

Background:

Papillary glioneuronal tumors (PGNTs) are rare, low-grade mixed neuronal-glial neoplasms of unclear etiology.
Typically considered benign and extraventricular, their behavior can be atypical.

Observation:

This article reviews clinicopathological and imaging characteristics of PGNTs.
It focuses on two cases with unusual recurrence after resection and intraventricular localization.
The study also examines advanced magnetic resonance imaging (MRI) techniques for PGNTs.

Findings:

PGNTs can exhibit recurrent behavior even after gross-total resection.
Intraventricular localization, though rare, is reported.
Advanced MRI techniques offer new insights into PGNT characteristics.

Implications:

Understanding atypical presentations of PGNTs is crucial for diagnosis and management.
Advanced MRI may improve characterization and monitoring of these rare tumors.
Further research is needed to elucidate the etiology and behavior of PGNTs.